Favorskii rearrangement mechanism and examples
Favorskii rearrangement reaction, examples, mechanism, quasi favorskii rearrangement and application have been discussed here. Favorskii rearrangement was first of all given by Favorski in 1894. Favorskii rearrangement Favorskii rearrangement is a base-catalyzed rearrangement of alpha-halo ketones to the carboxylic acid derivatives such as acids, esters, and amides. The product depends on the types of base […]
Cope rearrangement: Mechanism and examples
Cope rearrangement reaction, examples, mechanism, and its variations along with stereochemistry have been discussed here. Cope rearrangement is quite similar to claisen rearrangement, both are [3,3] sigmatropic rearrangement reactions. Cope rearrangement reaction Cope rearrangement is a thermal isomerization of a 1,5-diene through [3,3]-sigmatropic rearrangement giving a more stable 1,5-diene as a product. Let’s see an […]
Claisen Rearrangement: Mechanism and examples
Claisen rearrangement, examples, mechanism, and its application have been discussed here. The claisen rearrangement was first reported by Luduig Claisen in 1912. The claisen rearrangement Claisen rearrangement is the sigmatropic rearrangement of allyl vinyl ether or allyl aryl ethers to form γ,δ– unsaturated carbonyl compound or O-allyl substituted phenols respectively. Characteristics of Claisen rearrangement: Mostly these […]
Beckmann Rearrangement: Mechanism and application
Beckmann rearrangement reaction, examples, mechanism, and its application in organic chemistry have been discussed here. Beckmann rearrangement reaction was first reported by Beckmann in 1886. Beckmann rearrangement definition Oximes undergo a rearrangement reaction to give amide in presence of an acid catalyst. Such reaction is known as Beckmann rearrangement. In general, acid-catalyzed isomerization of oximes […]
Chromic acid oxidation: Mechanism and examples
Chromic acid oxidation, examples, mechanism, and some applications have been discussed here. Chromic acid oxidation is used for the oxidation of alcohols, aldehydes, and carbon-carbon double bonds in the hydrocarbons. Chromic acid has the formula H2CrO4 and has a structure as shown below. The chromic acid is generated during the reaction by mixing the following […]
Oppenauer oxidation: Mechanism and application
Oppenauer oxidation, examples, mechanism, and application have been discussed here. oppenauer oxidation definition The aluminum tri-isopropoxide catalyzed oxidation of secondary alcohol into ketones using another ketone or an aldehyde as the oxidant is called oppenauer oxidation reaction. Oppenauer oxidation is the reverse process of Meerwein-Ponndorf-Verley Reduction. Note: Oppenauer oxidation reaction does not affect carbon-carbon double […]
Baeyer villiger oxidation: Mechanism and application
Baeyer villiger oxidation reaction, examples, mechanism, and its applications have been discussed here. Baeyer villiger oxidation reaction The oxidation of ketones or aldehyde to ester in the presence of hydrogen peroxide or organic peroxides such as peroxy acids, perbenzoic acid, or peracetic acid is called the Baeyer villiger oxidation reaction. An acidic catalyst is required […]
Hydroboration oxidation: Mechanism and application
The hydroboration oxidation of alkene, alkynes, mechanism, and its application has been discussed here. Hydroboration oxidation When diborane reacts with alkenes, the addition of diborane to the carbon-carbon double bond takes place to form alkyl borane. This reaction is called hydroboration. On oxidation of alkyl borane with H2O2 in presence of NaOH gives alcohol as […]
Birch Reduction mechanism and application
Birch reduction mechanism, examples, and applications in organic chemistry have been discussed here. It is one of the famous dissolved metal reductions. The first thing to notice is that when lithium or sodium dissolves in ammonia, they produce a bright blue solution. The blue color is due to the solvated electrons. Birch reductions use those […]
How to read IR spectra: 7 easy steps
How to read IR spectra? Everybody has to face some difficulty while analyzing due to a lack of basic ways or tricks. If you don’t know about the basics of IR spectroscopy, you can read. Before discussing the basic idea to analyze the IR spectra, we must know about the regions present in the spectra. […]
How to read NMR spectra: 7 Trick or basic steps
To read an NMR spectrum of an organic compound, we must have basic knowledge about nuclear magnetic resonance spectroscopy. Do you know how the NMR spectra are generated? If not please visit our post on NMR spectroscopy. How to read NMR spectra? Ok, let’s move to our topic “how to read NMR spectra?”. We have […]
5 Laboratory emergency response plan: Do and don’ts in chemistry laboratory
We have tried to explain laboratory emergency and response plans as well as what do and don’ts in chemistry laboratory in this blog. Previously, we have discussed 10 preventive measures for chemical accidents. Although we apply all the preventive for our safety, sometimes we have to face an unexpected accident in the laboratory. What do […]